MEX3B inhibits collagen production in eosinophilic nasal polyps by downregulating epithelial cell TGFBR3 mRNA stability

Although the expression of Mex3 RNA-binding family member B (MEX3B) is upregulated in human nasal epithelial cells (HNECs) predominately in the eosinophilic chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) subtype, its functions as an RNA binding protein in airway epithelial cells remain unkn...

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Detalles Bibliográficos
Autores principales: Liu, Jin-Xin, Chen, Ao-Nan, Yu, Qihong, Shi, Ke-Tai, Liu, Yi-Bo, Guo, Cui-Lian, Wang, Zhe-Zheng, Yao, Yin, Pan, Li, Lu, Xiang, Xu, Kai, Wang, Heng, Zeng, Ming, Liu, Chaohong, Schleimer, Robert P., Wu, Ning, Liao, Bo, Liu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243817/
https://www.ncbi.nlm.nih.gov/pubmed/36976645
http://dx.doi.org/10.1172/jci.insight.159058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243817/
https://www.ncbi.nlm.nih.gov/pubmed/36976645
http://dx.doi.org/10.1172/jci.insight.159058

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