Impaired PPARγ activation by cadmium exacerbates infection-induced lung injury

Emerging data indicate an association between environmental heavy metal exposure and lung disease, including lower respiratory tract infections (LRTIs). Here, we show by single-cell RNA sequencing an increase in Pparg gene expression in lung macrophages from mice exposed to cadmium and/or infected w...

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Detalles Bibliográficos
Autores principales: Larson-Casey, Jennifer L., Liu, Shanrun, Pyles, Jennifer M., Lapi, Suzanne E., Saleem, Komal, Antony, Veena B., Gonzalez, Manuel Lora, Crossman, David K., Carter, A. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243824/
https://www.ncbi.nlm.nih.gov/pubmed/36928191
http://dx.doi.org/10.1172/jci.insight.166608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243824/
https://www.ncbi.nlm.nih.gov/pubmed/36928191
http://dx.doi.org/10.1172/jci.insight.166608

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