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Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1

Lipid regulation of ion channels is largely explored using in silico modeling with minimal experimentation in intact tissue; thus, the functional consequences of these predicted lipid-channel interactions within native cellular environments remain elusive. The goal of this study is to investigate ho...

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Detalles Bibliográficos
Autores principales: Ruddiman, Claire A., Peckham, Richard, Luse, Melissa A., Chen, Yen-Lin, Kuppusamy, Maniselvan, Corliss, Bruce A., Hall, P. Jordan, Lin, Chien-Jung, Peirce, Shayn M., Sonkusare, Swapnil K., Mecham, Robert P., Wagenseil, Jessica E., Isakson, Brant E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243826/
https://www.ncbi.nlm.nih.gov/pubmed/37014698
http://dx.doi.org/10.1172/jci.insight.165715