Local administration of mesenchymal stromal cells is safe and modulates the immune compartment in ulcerative proctitis

BACKGROUND: Due to their immunoregulatory and tissue regenerative features, mesenchymal stromal cells (MSCs) are a promising novel tool for the management of ulcerative proctitis (UP). Here we report on a phase IIa clinical study that evaluated the impact of local MSC therapy on UP. METHODS: Thirtee...

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Detalles Bibliográficos
Autores principales: Ouboter, Laura F., Barnhoorn, Marieke C., Verspaget, Hein W., Plug, Leonie, Pool, Emma S., Szuhai, Karoly, Hawinkels, Lukas J.A.C., van Pel, Melissa, Zwaginga, Jaap Jan, Roelen, Dave, Koning, Frits, Pascutti, M. Fernanda, van der Meulen – de Jong, Andrea E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243829/
https://www.ncbi.nlm.nih.gov/pubmed/36951952
http://dx.doi.org/10.1172/jci.insight.167402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243829/
https://www.ncbi.nlm.nih.gov/pubmed/36951952
http://dx.doi.org/10.1172/jci.insight.167402

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