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Aging alters mechanisms underlying voluntary movements in spinal motor neurons of mice, primates, and humans

Spinal motor neurons have been implicated in the loss of motor function that occurs with advancing age. However, the cellular and molecular mechanisms that impair the function of these neurons during aging remain unknown. Here, we show that motor neurons do not die in old female and male mice, rhesu...

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Detalles Bibliográficos
Autores principales: Castro, Ryan W., Lopes, Mikayla C., Settlage, Robert E., Valdez, Gregorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243831/
https://www.ncbi.nlm.nih.gov/pubmed/37154159
http://dx.doi.org/10.1172/jci.insight.168448