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Aging alters mechanisms underlying voluntary movements in spinal motor neurons of mice, primates, and humans
Spinal motor neurons have been implicated in the loss of motor function that occurs with advancing age. However, the cellular and molecular mechanisms that impair the function of these neurons during aging remain unknown. Here, we show that motor neurons do not die in old female and male mice, rhesu...
Autores principales: | Castro, Ryan W., Lopes, Mikayla C., Settlage, Robert E., Valdez, Gregorio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243831/ https://www.ncbi.nlm.nih.gov/pubmed/37154159 http://dx.doi.org/10.1172/jci.insight.168448 |
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