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Postprandial Increases in Liver-Gut Hormone LEAP2 Correlate with Attenuated Eating Behavior in Adults Without Obesity

BACKGROUND: The novel liver-gut hormone liver-expressed antimicrobial peptide-2 (LEAP2) is a centrally acting inverse agonist, and competitive antagonist of orexigenic acyl ghrelin (AG), at the GH secretagogue receptor, reducing food intake in rodents. In humans, the effects of LEAP2 on eating behav...

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Detalles Bibliográficos
Autores principales: Bhargava, Raghav, Luur, Sandra, Rodriguez Flores, Marcela, Emini, Mimoza, Prechtl, Christina G, Goldstone, Anthony P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243873/
https://www.ncbi.nlm.nih.gov/pubmed/37287649
http://dx.doi.org/10.1210/jendso/bvad061