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Postprandial Increases in Liver-Gut Hormone LEAP2 Correlate with Attenuated Eating Behavior in Adults Without Obesity
BACKGROUND: The novel liver-gut hormone liver-expressed antimicrobial peptide-2 (LEAP2) is a centrally acting inverse agonist, and competitive antagonist of orexigenic acyl ghrelin (AG), at the GH secretagogue receptor, reducing food intake in rodents. In humans, the effects of LEAP2 on eating behav...
Autores principales: | Bhargava, Raghav, Luur, Sandra, Rodriguez Flores, Marcela, Emini, Mimoza, Prechtl, Christina G, Goldstone, Anthony P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243873/ https://www.ncbi.nlm.nih.gov/pubmed/37287649 http://dx.doi.org/10.1210/jendso/bvad061 |
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