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Treatment of unmethylated MGMT-promoter recurrent glioblastoma with cancer stem cell assay-guided chemotherapy and the impact on patients’ healthcare costs

BACKGROUND: Glioblastoma (GBM) is a lethal disease. At least in part, the recurrence of GBM is caused by cancer stem cells (CSCs), which are resistant to chemotherapy. Personalized anticancer therapy against CSCs can improve treatment outcomes. We present a prospective cohort study of 40 real-world...

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Detalles Bibliográficos
Autores principales: Ranjan, Tulika, Yu, Alexander, Elhamdani, Shaed, Howard, Candace M, Lirette, Seth T, Denning, Krista L, Valluri, Jagan, Claudio, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243985/
https://www.ncbi.nlm.nih.gov/pubmed/37287692
http://dx.doi.org/10.1093/noajnl/vdad055