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Estimation of time-varying causal effects with multivariable Mendelian randomization: some cautionary notes

INTRODUCTION: For many exposures present across the life course, the effect of the exposure may vary over time. Multivariable Mendelian randomization (MVMR) is an approach that can assess the effects of related risk factors using genetic variants as instrumental variables. Recently, MVMR has been us...

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Detalles Bibliográficos
Autores principales: Tian, Haodong, Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244034/
https://www.ncbi.nlm.nih.gov/pubmed/36661066
http://dx.doi.org/10.1093/ije/dyac240