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Psychedelics promote plasticity by directly binding to BDNF receptor TrkB

Psychedelics produce fast and persistent antidepressant effects and induce neuroplasticity resembling the effects of clinically approved antidepressants. We recently reported that pharmacologically diverse antidepressants, including fluoxetine and ketamine, act by binding to TrkB, the receptor for B...

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Detalles Bibliográficos
Autores principales: Moliner, Rafael, Girych, Mykhailo, Brunello, Cecilia A., Kovaleva, Vera, Biojone, Caroline, Enkavi, Giray, Antenucci, Lina, Kot, Erik F., Goncharuk, Sergey A., Kaurinkoski, Katja, Kuutti, Mirjami, Fred, Senem M., Elsilä, Lauri V., Sakson, Sven, Cannarozzo, Cecilia, Diniz, Cassiano R. A. F., Seiffert, Nina, Rubiolo, Anna, Haapaniemi, Hele, Meshi, Elsa, Nagaeva, Elina, Öhman, Tiina, Róg, Tomasz, Kankuri, Esko, Vilar, Marçal, Varjosalo, Markku, Korpi, Esa R., Permi, Perttu, Mineev, Konstantin S., Saarma, Mart, Vattulainen, Ilpo, Casarotto, Plinio C., Castrén, Eero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244169/
https://www.ncbi.nlm.nih.gov/pubmed/37280397
http://dx.doi.org/10.1038/s41593-023-01316-5