A novel patient-derived 3D model recapitulates mantle cell lymphoma lymph node signaling, immune profile and in vivo ibrutinib responses

Mantle cell lymphoma (MCL), a rare and aggressive B-cell non-Hodgkin lymphoma, mainly develops in the lymph node (LN) and creates a protective and immunosuppressive niche that facilitates tumor survival, proliferation and chemoresistance. To capture disease heterogeneity and tumor microenvironment (...

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Detalles Bibliográficos
Autores principales: Araujo-Ayala, Ferran, Dobaño-López, Cèlia, Valero, Juan García, Nadeu, Ferran, Gava, Fabien, Faria, Carla, Norlund, Marine, Morin, Renaud, Bernes-Lasserre, Pascale, Serrat, Neus, Playa-Albinyana, Heribert, Giménez, Rubén, Campo, Elías, Lagarde, Jean-Michel, López-Guillermo, Armando, Gine, Eva, Colomer, Dolors, Bezombes, Christine, Pérez-Galán, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244172/
https://www.ncbi.nlm.nih.gov/pubmed/37031299
http://dx.doi.org/10.1038/s41375-023-01885-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244172/
https://www.ncbi.nlm.nih.gov/pubmed/37031299
http://dx.doi.org/10.1038/s41375-023-01885-1

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