Biological and clinical implications of FGFR aberrations in paediatric and young adult cancers

Rare but recurrent mutations in the fibroblast growth factor receptor (FGFR) pathways, most commonly in one of the four FGFR receptor tyrosine kinase genes, can potentially be targeted with broad-spectrum multi-kinase or FGFR selective inhibitors. The complete spectrum of these mutations in paediatr...

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Detalles Bibliográficos
Autores principales: Brown, Lauren M., Ekert, Paul G., Fleuren, Emmy D. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244177/
https://www.ncbi.nlm.nih.gov/pubmed/37130917
http://dx.doi.org/10.1038/s41388-023-02705-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244177/
https://www.ncbi.nlm.nih.gov/pubmed/37130917
http://dx.doi.org/10.1038/s41388-023-02705-7

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