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Hyperglycemia-Suppressed SMARCA5 Disrupts Transcriptional Homeostasis to Facilitate Endothelial Dysfunction in Diabetes

BACKGROUND: Dysfunction of vascular endothelial cells (ECs) plays a central role in the pathogenesis of cardiovascular complications in diabetes. SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) is a key regulator of chromatin structure and DNA...

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Detalles Bibliográficos
Autores principales: Wang, Ju, Zhou, Hui, Shao, Jinhua, Zhang, Shu, Jin, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244191/
https://www.ncbi.nlm.nih.gov/pubmed/36872061
http://dx.doi.org/10.4093/dmj.2022.0179