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Hyperglycemia-Suppressed SMARCA5 Disrupts Transcriptional Homeostasis to Facilitate Endothelial Dysfunction in Diabetes
BACKGROUND: Dysfunction of vascular endothelial cells (ECs) plays a central role in the pathogenesis of cardiovascular complications in diabetes. SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) is a key regulator of chromatin structure and DNA...
Autores principales: | Wang, Ju, Zhou, Hui, Shao, Jinhua, Zhang, Shu, Jin, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244191/ https://www.ncbi.nlm.nih.gov/pubmed/36872061 http://dx.doi.org/10.4093/dmj.2022.0179 |
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