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Berberine alleviates non-alcoholic hepatic steatosis partially by promoting SIRT1 deacetylation of CPT1A in mice

BACKGROUND: Berberine effectively alleviates non-alcoholic fatty liver disease (NAFLD). Nevertheless, the mechanism is incompletely comprehended. It has been reported that SIRT1 mediates lipid metabolism in liver and berberine promotes the expression of SIRT1 in hepatocytes. We hypothesized that SIR...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Li, Ruikai, Li, Yuqi, Tan, Siwei, Jiang, Jie, Liu, Huiling, Wei, Xiuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244209/
https://www.ncbi.nlm.nih.gov/pubmed/37293270
http://dx.doi.org/10.1093/gastro/goad032