Human calmodulin mutations cause arrhythmia and affect neuronal function in C. elegans

In humans, mutations in calmodulin cause cardiac arrhythmia. These mutations disrupt the ability of calmodulin to sense calcium concentrations and correctly regulate two central calcium channels, together obstructing heart rhythm. This correlation is well established, but also surprising since calmo...

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Detalles Bibliográficos
Autores principales: Jensen, Helene H, Frantzen, Magnus T, Wesseltoft, Jonas L, Busuioc, Ana-Octavia, Møller, Katrine V, Brohus, Malene, Duun, Palle R, Nyegaard, Mette, Overgaard, Michael T, Olsen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244212/
https://www.ncbi.nlm.nih.gov/pubmed/36920509
http://dx.doi.org/10.1093/hmg/ddad042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244212/
https://www.ncbi.nlm.nih.gov/pubmed/36920509
http://dx.doi.org/10.1093/hmg/ddad042

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