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Opposite modulation of functional recovery following contusive spinal cord injury in mice with oligodendrocyte-selective deletions of Atf4 and Chop/Ddit3
The integrated stress response (ISR)-activated transcription factors ATF4 and CHOP/DDIT3 may regulate oligodendrocyte (OL) survival, tissue damage and functional impairment/recovery in white matter pathologies, including traumatic spinal cord injury (SCI). Accordingly, in OLs of OL-specific RiboTag...
Autores principales: | Gao, Yonglin, Wei, George Z., Forston, Michael D., Rood, Benjamin, Hodges, Emily R., Burke, Darlene, Andres, Kariena, Morehouse, Johnny, Armstrong, Christine, Glover, Charles, Slomnicki, Lukasz P., Ding, Jixiang, Chariker, Julia H., Rouchka, Eric C., Saraswat Ohri, Sujata, Whittemore, Scott R., Hetman, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244317/ https://www.ncbi.nlm.nih.gov/pubmed/37280306 http://dx.doi.org/10.1038/s41598-023-36258-2 |
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