Platelets from patients with myeloproliferative neoplasms have increased numbers of mitochondria that are hypersensitive to depolarization by thrombin

Thrombosis is one of the cardinal manifestations of myeloproliferative neoplasms (MPN). The mechanisms leading to a prothrombotic state in MPN are complex and remain poorly understood. Platelet mitochondria play a role in platelet activation, but their number and function have not been extensively e...

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Detalles Bibliográficos
Autores principales: Ross, David M., Liang, Hai Po Helena, Iqra, Zeenet, Whittaker, Shane, Tan, Chuen Wen, Dale, Brian J., Chen, Vivien M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244326/
https://www.ncbi.nlm.nih.gov/pubmed/37280424
http://dx.doi.org/10.1038/s41598-023-36266-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244326/
https://www.ncbi.nlm.nih.gov/pubmed/37280424
http://dx.doi.org/10.1038/s41598-023-36266-2

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