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Establishment and characterization of patient-derived xenograft of a rare pediatric anaplastic pleomorphic xanthoastrocytoma (PXA) bearing a CDC42SE2-BRAF fusion

Pleomorphic xanthoastrocytoma (PXA) is a rare subset of primary pediatric glioma with 70% 5-year disease free survival. However, up to 20% of cases present with local recurrence and malignant transformation into more aggressive type anaplastic PXA (AXPA) or glioblastoma. The understanding of disease...

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Detalles Bibliográficos
Autores principales: Damayanti, Nur P., Saadatzadeh, M. Reza, Dobrota, Erika, Ordaz, Josue D., Bailey, Barbara J., Pandya, Pankita H., Bijangi-Vishehsaraei, Khadijeh, Shannon, Harlan E., Alfonso, Anthony, Coy, Kathy, Trowbridge, Melissa, Sinn, Anthony L., Zhang, Zhong-Yin, Gallagher, Rosa I., Wulfkuhle, Julia, Petricoin, Emanuel, Richardson, Angela M., Marshall, Mark S., Lion, Alex, Ferguson, Michael J., Balsara, Karl E., Pollok, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244396/
https://www.ncbi.nlm.nih.gov/pubmed/37280243
http://dx.doi.org/10.1038/s41598-023-36107-2