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Adult-born neurons in critical period maintain hippocampal seizures via local aberrant excitatory circuits

Temporal lobe epilepsy (TLE), one common type of medically refractory epilepsy, is accompanied with altered adult-born dentate granule cells (abDGCs). However, the causal role of abDGCs in recurrent seizures of TLE is not fully understood. Here, taking advantage of optogenetic and chemogenetic tools...

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Detalles Bibliográficos
Autores principales: Chen, Liying, Xu, Yingwei, Cheng, Heming, Li, Zhongxia, Lai, Nanxi, Li, Menghan, Ruan, Yeping, Zheng, Yang, Fei, Fan, Xu, Cenglin, Ma, Jiao, Wang, Shuang, Gu, Yan, Han, Feng, Chen, Zhong, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244397/
https://www.ncbi.nlm.nih.gov/pubmed/37280192
http://dx.doi.org/10.1038/s41392-023-01433-4