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Adult-born neurons in critical period maintain hippocampal seizures via local aberrant excitatory circuits
Temporal lobe epilepsy (TLE), one common type of medically refractory epilepsy, is accompanied with altered adult-born dentate granule cells (abDGCs). However, the causal role of abDGCs in recurrent seizures of TLE is not fully understood. Here, taking advantage of optogenetic and chemogenetic tools...
Autores principales: | Chen, Liying, Xu, Yingwei, Cheng, Heming, Li, Zhongxia, Lai, Nanxi, Li, Menghan, Ruan, Yeping, Zheng, Yang, Fei, Fan, Xu, Cenglin, Ma, Jiao, Wang, Shuang, Gu, Yan, Han, Feng, Chen, Zhong, Wang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244397/ https://www.ncbi.nlm.nih.gov/pubmed/37280192 http://dx.doi.org/10.1038/s41392-023-01433-4 |
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