Cargando…

SIM2s directed Parkin-mediated mitophagy promotes mammary epithelial cell differentiation

The functionally differentiated mammary gland adapts to extreme levels of stress from increased demand for energy by activating specific protective mechanisms to support neonatal health. Here, we identify the breast tumor suppressor gene, single-minded 2 s (SIM2s) as a novel regulator of mitophagy,...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanchez, Lilia, Epps, Jessica, Wall, Steven, McQueen, Cole, Pearson, Scott J., Scribner, Kelly, Wellberg, Elizabeth A., Giles, Erin D., Rijnkels, Monique, Porter, Weston W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244402/
https://www.ncbi.nlm.nih.gov/pubmed/36966227
http://dx.doi.org/10.1038/s41418-023-01146-9