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AGER1 deficiency-triggered ferroptosis drives fibrosis progression in nonalcoholic steatohepatitis with type 2 diabetes mellitus

Hyperglycemia is an independent risk factor for the rapid progression of nonalcoholic steatohepatitis (NASH) to liver fibrosis with an incompletely defined mechanism. Ferroptosis is a novel form of programmed cell death that has been identified as a pathogenic mechanism in various diseases. However,...

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Detalles Bibliográficos
Autores principales: Gong, Yihui, Liu, Zijun, Zhang, Yuanyuan, Zhang, Jun, Zheng, Yin, Wu, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244405/
https://www.ncbi.nlm.nih.gov/pubmed/37280194
http://dx.doi.org/10.1038/s41420-023-01477-z