Hyperglycemia-activated 11β-hydroxysteroid dehydrogenase type 1 increases endoplasmic reticulum stress and skin barrier dysfunction

The diabetes mellitus (DM) skin shows skin barrier dysfunction and skin lipid abnormality, similar to conditions induced by systemic or local glucocorticoid excess and aged skin. Inactive glucocorticoid (GC) is converted into active glucocorticoid by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1...

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Detalles Bibliográficos
Autores principales: Lee, Young Bin, Hwang, Hyun Jee, Kim, Eunjung, Lim, Sung Ha, Chung, Choon Hee, Choi, Eung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244460/
https://www.ncbi.nlm.nih.gov/pubmed/37280272
http://dx.doi.org/10.1038/s41598-023-36294-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244460/
https://www.ncbi.nlm.nih.gov/pubmed/37280272
http://dx.doi.org/10.1038/s41598-023-36294-y

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