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A lyophilized surfactant-based rutin formulation with improved physical characteristics and dissolution for oral delivery

Rutin (RUT) is a phytochemical flavonoid with numerous therapeutic potentials including antihypertension, cardioprotective, neuroprotective, and anti-cancer activities. Its clinical use is inhibited due to its poor aqueous solubility and permeability over oral administration. The present study aimed...

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Detalles Bibliográficos
Autores principales: Yusuf, Helmy, Meidy Nurintan Savitri, Orchidea, Primaharinastiti, Riesta, Agus Syamsur Rijal, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244468/
https://www.ncbi.nlm.nih.gov/pubmed/37293379
http://dx.doi.org/10.1016/j.jsps.2023.03.018