Lipoprotein(a) induces caspase-1 activation and IL-1 signaling in human macrophages

INTRODUCTION: Lipoprotein(a) (Lp(a)) is an LDL-like particle with an additional apolipoprotein (apo)(a) covalently attached. Elevated levels of circulating Lp(a) are a risk factor for atherosclerosis. A proinflammatory role for Lp(a) has been proposed, but its molecular details are incompletely defi...

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Detalles Bibliográficos
Autores principales: Lorey, Martina B., Youssef, Amer, Äikäs, Lauri, Borrelli, Matthew, Hermansson, Martin, Assini, Julia M., Kemppainen, Aapeli, Ruhanen, Hanna, Ruuth, Maija, Matikainen, Sampsa, Kovanen, Petri T., Käkelä, Reijo, Boffa, Michael B., Koschinsky, Marlys L., Öörni, Katariina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244518/
https://www.ncbi.nlm.nih.gov/pubmed/37293282
http://dx.doi.org/10.3389/fcvm.2023.1130162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244518/
https://www.ncbi.nlm.nih.gov/pubmed/37293282
http://dx.doi.org/10.3389/fcvm.2023.1130162

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