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Detecting and measuring of GPCR signaling – comparison of human induced pluripotent stem cells and immortal cell lines

G protein-coupled receptors (GPCRs) are a large family of transmembrane proteins that play a major role in many physiological processes, and thus GPCR-targeted drug development has been widely promoted. Although research findings generated in immortal cell lines have contributed to the advancement o...

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Detalles Bibliográficos
Autores principales: Chen, Gaoxian, Obal, Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244570/
https://www.ncbi.nlm.nih.gov/pubmed/37293485
http://dx.doi.org/10.3389/fendo.2023.1179600