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Evaluating the role of selection in the evolution of mitochondrial genomes of aboriginal peoples of Siberia

Studies of the nature of mitochondrial DNA (mtDNA) variability in human populations have shown that protein-coding genes are under negative (purifying) selection, since their mutation spectra are characterized by a pronounced predominance of synonymous substitutions over non-synonymous ones (Ka/Ks &...

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Detalles Bibliográficos
Autores principales: Malyarchuk, B.A., Derenko, M.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244587/
https://www.ncbi.nlm.nih.gov/pubmed/37293444
http://dx.doi.org/10.18699/VJGB-23-28