Programmable RNA editing with endogenous ADAR enzymes – a feasible option for the treatment of inherited retinal disease?

RNA editing holds great promise for the therapeutic correction of pathogenic, single nucleotide variants (SNV) in the human transcriptome since it does not risk creating permanent off-targets edits in the genome and has the potential for innovative delivery options. Adenine deaminases acting on RNA...

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Detalles Bibliográficos
Autores principales: Bellingrath, Julia-Sophia, McClements, Michelle E., Fischer, M. Dominik, MacLaren, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244592/
https://www.ncbi.nlm.nih.gov/pubmed/37293541
http://dx.doi.org/10.3389/fnmol.2023.1092913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244592/
https://www.ncbi.nlm.nih.gov/pubmed/37293541
http://dx.doi.org/10.3389/fnmol.2023.1092913

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