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Programmable RNA editing with endogenous ADAR enzymes – a feasible option for the treatment of inherited retinal disease?
RNA editing holds great promise for the therapeutic correction of pathogenic, single nucleotide variants (SNV) in the human transcriptome since it does not risk creating permanent off-targets edits in the genome and has the potential for innovative delivery options. Adenine deaminases acting on RNA...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244592/ https://www.ncbi.nlm.nih.gov/pubmed/37293541 http://dx.doi.org/10.3389/fnmol.2023.1092913 |