X-ray crystallography and sickle cell disease drug discovery—a tribute to Donald Abraham

X-ray crystallography and structure-based drug discovery have played a major role in the discovery of antisickling agents that target hemoglobin (Hb) for the treatment of sickle cell disease (SCD). Sickle cell disease, the most common inherited hematologic disorder, occurs as a result of a single po...

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Detalles Bibliográficos
Autores principales: Donkor, Akua K., Pagare, Piyusha P., Mughram, Mohammed H. AL, Safo, Martin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244664/
https://www.ncbi.nlm.nih.gov/pubmed/37293554
http://dx.doi.org/10.3389/fmolb.2023.1136970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244664/
https://www.ncbi.nlm.nih.gov/pubmed/37293554
http://dx.doi.org/10.3389/fmolb.2023.1136970

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