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Ovalbumin-specific CD4(+) and CD8(+) T cells contribute to different susceptibility for Theiler’s murine encephalomyelitis virus persistence

Theiler’s murine encephalomyelitis virus (TMEV) is the causative agent of TMEV-induced demyelinating disease (TMEV-IDD); a well-established animal model for the chronic progressive form of human multiple sclerosis (MS). In susceptible mice with an inadequate immune response, TMEV-IDD is triggered by...

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Detalles Bibliográficos
Autores principales: Wannemacher, Rouven, Reiß, Anna, Rohn, Karl, Lühder, Fred, Flügel, Alexander, Baumgärtner, Wolfgang, Hülskötter, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244668/
https://www.ncbi.nlm.nih.gov/pubmed/37292191
http://dx.doi.org/10.3389/fimmu.2023.1194842