Cargando…

IL11 activates the placental inflammasome to drive preeclampsia

INTRODUCTION: Preeclampsia is a life-threatening disorder of pregnancy unique to humans. Interleukin (IL)11 is elevated in serum from pregnancies that subsequently develop early-onset preeclampsia and pharmacological elevation of IL11 in pregnant mice causes the development of early-onset preeclamps...

Descripción completa

Detalles Bibliográficos
Autores principales: Menkhorst, Ellen, Santos, Leilani L., Zhou, Wei, Yang, Guannan, Winship, Amy L., Rainczuk, Katarzyna E., Nguyen, Philana, Zhang, Jian-Guo, Moore, Paddy, Williams, Michelle, Lê Cao, Kim-Anh, Mansell, Ashley, Dimitriadis, Evdokia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244672/
https://www.ncbi.nlm.nih.gov/pubmed/37292200
http://dx.doi.org/10.3389/fimmu.2023.1175926