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Integrated high-throughput analysis identifies super enhancers in metastatic castration-resistant prostate cancer

Background: Metastatic castration-resistant prostate cancer (mCRPC) is a highly aggressive stage of prostate cancer, and non-mutational epigenetic reprogramming plays a critical role in its progression. Super enhancers (SE), epigenetic elements, are involved in multiple tumor-promoting signaling pat...

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Detalles Bibliográficos
Autores principales: Zeng, Jie, Chen, Jiahong, Li, Maozhang, Zhong, Chuanfan, Liu, Zezhen, Wang, Yan, Li, Yuejiao, Jiang, Funeng, Fang, Shumin, Zhong, Weide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244677/
https://www.ncbi.nlm.nih.gov/pubmed/37292153
http://dx.doi.org/10.3389/fphar.2023.1191129