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Bacteroides dorei BDX-01 alleviates DSS-induced experimental colitis in mice by regulating intestinal bile salt hydrolase activity and the FXR-NLRP3 signaling pathway

Background: The relationships among intestinal dysbiosis, bile acid (BA) metabolism disorders, and ulcerative colitis pathogenesis are now recognized. However, how specific strains regulate BA metabolism to alleviate colitis is still unclear. This study investigated the effects of Bacteroides dorei...

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Detalles Bibliográficos
Autores principales: Sun, Xiaowei, Chen, Zhenhui, Yu, Lu, Zeng, Weisen, Sun, Boyuan, Fan, Hongying, Bai, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244678/
https://www.ncbi.nlm.nih.gov/pubmed/37292154
http://dx.doi.org/10.3389/fphar.2023.1205323