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Bone morphogenetic protein-7 attenuates pancreatic damage under diabetic conditions and prevents progression to diabetic nephropathy via inhibition of ferroptosis

BACKGROUND: Approximately 30% of diabetic patients develop diabetic nephropathy, a representative microvascular complication. Although the etiological mechanism has not yet been fully elucidated, renal tubular damage by hyperglycemia-induced expression of transforming growth factor-β (TGF-β) is know...

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Detalles Bibliográficos
Autores principales: Song, Sang Hyun, Han, Dawool, Park, Kyeonghui, Um, Jo Eun, Kim, Seonghun, Ku, Minhee, Yang, Jaemoon, Yoo, Tae-Hyun, Yook, Jong In, Kim, Nam Hee, Kim, Hyun Sil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244744/
https://www.ncbi.nlm.nih.gov/pubmed/37293506
http://dx.doi.org/10.3389/fendo.2023.1172199