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Epithelial cells sense local stiffness via Piezo1 mediated cytoskeletal reorganization

Local substrate stiffness is one of the major mechanical inputs for tissue organization during its development and remodeling. It is widely recognized that adherent cells use transmembrane proteins (integrins) at focal adhesions to translate ECM mechanical cues into intracellular bioprocess. Here we...

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Detalles Bibliográficos
Autores principales: Jetta, Deekshitha, Shireen, Tasnim, Hua, Susan Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244755/
https://www.ncbi.nlm.nih.gov/pubmed/37293127
http://dx.doi.org/10.3389/fcell.2023.1198109