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Endogenous reactive oxygen species and nitric oxide have opposite roles in regulating HIF-1alpha expression in hypoxic astrocytes

Ischemic stroke results in cerebral tissue hypoxia and increased expression of hypoxia-inducible factor (HIF), which is critically implicated in ischemic brain injury. Understanding the mechanisms of HIF-1alpha regulation in the ischemic brain has been an important research focus. The generation of...

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Detalles Bibliográficos
Autores principales: Chen, Qingquan, Liu, Wenlan, Sun, Xi, Liu, Ke Jian, Pan, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biophysics Reports Editorial Office 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244794/
https://www.ncbi.nlm.nih.gov/pubmed/37287488
http://dx.doi.org/10.52601/bpr.2021.200016