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Prominin‐1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice

PURPOSE: Spermatogenesis is a complex process orchestrated by several essential genes. Prominin‐1 (Prom1/PROM1) is a gene that is expressed in the testis but with a poorly understood role in spermatogenesis. METHODS: We used Prom1 knockout (Prom1 KO) mice to assess the role of Prom1 in spermatogenes...

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Detalles Bibliográficos
Autores principales: Matsukuma, Haruka, Kobayashi, Yuka, Oka, Shintaro, Higashijima, Fumiaki, Kimura, Kazuhiro, Yoshihara, Erika, Sasai, Noriaki, Shiraishi, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244806/
https://www.ncbi.nlm.nih.gov/pubmed/37292088
http://dx.doi.org/10.1002/rmb2.12514