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Neurosteroid pathway derangement in asphyctic infants treated with hypothermia: an untargeted metabolomic approach

BACKGROUND: The pathobiological mechanisms associated with perinatal asphyxia and hypoxic-ischemic encephalopathy are complex and poorly understood. The metabolic effects of therapeutic hypothermia have been partially explored. METHODS: We conducted a single-center longitudinal study to investigate...

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Detalles Bibliográficos
Autores principales: Valerio, Enrico, Stocchero, Matteo, Pirillo, Paola, D’Errico, Ignazio, Bonadies, Luca, Galderisi, Alfonso, Giordano, Giuseppe, Baraldi, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244906/
https://www.ncbi.nlm.nih.gov/pubmed/37257315
http://dx.doi.org/10.1016/j.ebiom.2023.104636