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Hypoxia‐inducible factor 1A inhibition overcomes castration resistance of prostate tumors

Androgen deprivation therapy (ADT) is a cornerstone of prostate cancer (PCa) management. Although tumors initially regress, many progress to a hormone‐independent state termed castration‐resistant PCa (CRPC), for which treatment options are limited. We here report that the major luminal cell populat...

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Detalles Bibliográficos
Autores principales: Terzic, Julie, Abu el Maaty, Mohamed A, Lutzing, Régis, Vincent, Alexandre, El Bizri, Rana, Jung, Matthieu, Keime, Céline, Metzger, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245031/
https://www.ncbi.nlm.nih.gov/pubmed/37070472
http://dx.doi.org/10.15252/emmm.202217209