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Oxidative stress enhances the therapeutic action of a respiratory inhibitor in MYC‐driven lymphoma

MYC is a key oncogenic driver in multiple tumor types, but concomitantly endows cancer cells with a series of vulnerabilities that provide opportunities for targeted pharmacological intervention. For example, drugs that suppress mitochondrial respiration selectively kill MYC‐overexpressing cells. He...

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Detalles Bibliográficos
Autores principales: Donati, Giulio, Nicoli, Paola, Verrecchia, Alessandro, Vallelonga, Veronica, Croci, Ottavio, Rodighiero, Simona, Audano, Matteo, Cassina, Laura, Ghsein, Aya, Binelli, Giorgio, Boletta, Alessandra, Mitro, Nico, Amati, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245039/
https://www.ncbi.nlm.nih.gov/pubmed/37158102
http://dx.doi.org/10.15252/emmm.202216910