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Construction and validation of customized genomes for human and mouse ribosomal DNA mapping

rRNAs are transcribed from ribosomal DNA (rDNA) repeats, the most intensively transcribed loci in the genome. Due to their repetitive nature, there is a lack of genome assemblies suitable for rDNA mapping, creating a vacuum in our understanding of how the most abundant RNA in the cell is regulated....

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Detalles Bibliográficos
Autores principales: George, Subin S., Pimkin, Maxim, Paralkar, Vikram R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245113/
https://www.ncbi.nlm.nih.gov/pubmed/37121547
http://dx.doi.org/10.1016/j.jbc.2023.104766