The mammalian peroxisomal membrane is permeable to both GSH and GSSG – Implications for intraperoxisomal redox homeostasis

Despite the large amounts of H(2)O(2) generated in mammalian peroxisomes, cysteine residues of intraperoxisomal proteins are maintained in a reduced state. The biochemistry behind this phenomenon remains unexplored, and simple questions such as “is the peroxisomal membrane permeable to glutathione?”...

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Detalles Bibliográficos
Autores principales: Ferreira, Maria J., Rodrigues, Tony A., Pedrosa, Ana G., Gales, Luís, Salvador, Armindo, Francisco, Tânia, Azevedo, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245115/
https://www.ncbi.nlm.nih.gov/pubmed/37257275
http://dx.doi.org/10.1016/j.redox.2023.102764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245115/
https://www.ncbi.nlm.nih.gov/pubmed/37257275
http://dx.doi.org/10.1016/j.redox.2023.102764

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