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Deficiency in hereditary hemorrhagic telangiectasia-associated Endoglin elicits hypoxia-driven heart failure in zebrafish

Hereditary hemorrhagic telangiectasia (HHT) is a rare genetic disease caused by mutations affecting components of bone morphogenetic protein (BMP)/transforming growth factor-β (TGF-β) signaling in endothelial cells. This disorder is characterized by arteriovenous malformations that are prone to rupt...

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Detalles Bibliográficos
Autores principales: Lelièvre, Etienne, Bureau, Charlotte, Bordat, Yann, Frétaud, Maxence, Langevin, Christelle, Jopling, Chris, Kissa, Karima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245139/
https://www.ncbi.nlm.nih.gov/pubmed/37264878
http://dx.doi.org/10.1242/dmm.049488