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Preparations and characterizations of effervescent granules containing azithromycin solid dispersion for children and elder: Solubility enhancement, taste-masking, and digestive acidic protection

Azithromycin, a macrolide antibiotics, is one of the frequently used drugs in the children and elder. However, due to these population difficulty in swallowing and inefficient absorption, and azithromycin inherent poor solubility, bitter taste, and instability in the stomach acidic condition, it is...

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Detalles Bibliográficos
Autores principales: Huynh, Duyen Thi My, Hai, Huynh Thien, Hau, Nguyen Minh, Lan, Huynh Kim, Vinh, Truong Phu, Tran, Van De, Pham, Duy Toan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245243/
https://www.ncbi.nlm.nih.gov/pubmed/37292293
http://dx.doi.org/10.1016/j.heliyon.2023.e16592