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Effects of Local Anesthetics on Liposomal Membranes Determined by Their Inhibitory Activity of Lipid Peroxidation

[Image: see text] In this study, we investigated the effects of drugs on membrane function in which lipid peroxidation was inhibited by the antioxidant Trolox (TRO) in liposomes containing egg yolk lecithin. Local anesthetics (LAs), such as lidocaine (LID) and dibucaine (DIB), were used as model dru...

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Detalles Bibliográficos
Autores principales: Horizumi, Yusuke, Goto, Satoru, Takatsuka, Miwa, Yokoyama, Hideshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245376/
https://www.ncbi.nlm.nih.gov/pubmed/37104048
http://dx.doi.org/10.1021/acs.molpharmaceut.2c01053