Fed- and Fasted-State Performance of Pretomanid Amorphous Solid Dispersions Formulated with an Enteric Polymer

[Image: see text] Weakly acid polymers with pH-responsive solubility are being used with increasing frequency in amorphous solid dispersion (ASD) formulations of drugs with low aqueous solubility. However, drug release and crystallization in a pH environment where the polymer is insoluble are not we...

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Detalles Bibliográficos
Autores principales: Nguyen, Hanh Thuy, Van Duong, Tu, Jaw-Tsai, Sarah, Bruning-Barry, Rebecca, Pande, Poonam, Taneja, Rajneesh, Taylor, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245392/
https://www.ncbi.nlm.nih.gov/pubmed/37220082
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245392/
https://www.ncbi.nlm.nih.gov/pubmed/37220082
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00174

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