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Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis
BACKGROUND: Silica-induced pulmonary fibrosis (silicosis) is a diffuse interstitial fibrotic disease characterized by the massive deposition of extracellular matrix in lung tissue. Fibroblast to myofibroblast differentiation is crucial for the disease progression. Inhibiting myofibroblast differenti...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245413/ https://www.ncbi.nlm.nih.gov/pubmed/37280614 http://dx.doi.org/10.1186/s12967-023-04241-0 |